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Henrietta Lacks is an individual who has had a profound impact on the fields of science, medicine, and ethics. Her story is one that highlights the complex intersection of race, medical research, and patient rights. Henrietta Lacks was an African American woman who unknowingly made an enduring contribution to medical science through the extraction and propagation of her cells, now widely known as the HeLa cells. These cells have been instrumental in numerous medical breakthroughs and advancements, yet Lacks and her family were unaware of their existence and the massive implications they would have. This introduction will delve into the life of Henrietta Lacks, her unknowing contribution to science, and the ethical dilemmas her story raises.
(1920-1951)
Who Is Henrietta Lacks?
Henrietta Lacks was born in 1920 in Virginia and died of cervical cancer in 1951. Cells taken from her body without her knowledge were used to form the HeLa cell line, which has been used extensively in medical research since that time. Lacks’ case has sparked legal and ethical debates over the rights of an individual to his or her genetic material and tissue.
Early Life
Lacks was born Loretta Pleasant on August 1, 1920, in Roanoke, Virginia. At some point, she changed her name to Henrietta. After the death of her mother in 1924, Henrietta was sent to live with her grandfather in a log cabin that had been the slave quarters of a white ancestor’s plantation. Henrietta Lacks shared a room with her first cousin, David “Day” Lacks.
In 1935, the cousins had a son they called Lawrence. Henrietta was 14. The couple had a daughter, Elsie, in 1939, and married in 1941. Henrietta and David moved to Maryland at the urging of another cousin, Fred Garret. There, they had three more children: David Jr., Deborah and Joseph. They placed their daughter Elsie, who was developmentally disabled, in the Hospital for the Negro Insane.
Death
On January 29, 1951, Lacks went to Johns Hopkins Hospital to diagnose abnormal pain and bleeding in her abdomen. Physician Howard Jones quickly diagnosed her with cervical cancer.
During her subsequent radiation treatments, doctors removed two cervical samples from Lacks without her knowledge. She died at Johns Hopkins on October 4, 1951, at the age of 31.
HeLa Cells
The cells from Lacks’s tumor made their way to the laboratory of researcher Dr. George Otto Gey. Gey noticed an unusual quality in the cells. Unlike most cells, which survived only a few days, Lacks’s cells were far more durable.
Gey isolated and multiplied a specific cell, creating a cell line. He dubbed the resulting sample HeLa, derived from the name Henrietta Lacks.
The HeLa strain revolutionized medical research. Jonas Salk used the HeLa strain to develop the polio vaccine, sparking mass interest in the cells. As demand grew, scientists cloned the cells in 1955.
Since that time, over ten thousand patents involving HeLa cells have been registered. Researchers have used the cells to study disease and to test human sensitivity to new products and substances.
Johns Hopkins Statement
In February 2010, Johns Hopkins released the following statement concerning the cervical samples that were taken from Lacks without her consent:
“Johns Hopkins Medicine sincerely acknowledges the contribution to advances in biomedical research made possible by Henrietta Lacks and HeLa cells. It’s important to note that at the time the cells were taken from Mrs. Lacks’ tissue, the practice of obtaining informed consent from cell or tissue donors was essentially unknown among academic medical centers. Sixty years ago, there was no established practice of seeking permission to take tissue for scientific research purposes. The laboratory that received Mrs. Lacks’s cells had arranged many years earlier to obtain such cells from any patient diagnosed with cervical cancer as a way to learn more about a serious disease that took the lives of so many. Johns Hopkins never patented HeLa cells, nor did it sell them commercially or benefit in a direct financial way. Today, Johns Hopkins and other research-based medical centers consistently obtain consent from those asked to donate tissue or cells for scientific research.”
‘The Immortal Life of Henrietta Lacks’
The Lacks family learned about the HeLa cells in the 1970s. In 1973, a scientist contacted family members, seeking blood samples and other genetic materials–but inquiries from the family regarding the use of HeLa cells, and publications that included their own genetic information, were largely ignored.
The case gained new visibility in 1998, when the BBC screened an award-winning documentary on Lacks and HeLa. Rebecca Skloot later wrote a popular book on the subject, called The Immortal Life of Henrietta Lacks.
Oprah Winfrey and HBO announced plans to develop a film based on Skloot’s 2010 book and in 2017, the network aired the biopic. Lacks’ sons David Lacks, Jr. and Zakariyya Rahman, and granddaughter Jeri Lacks consulted on the film and Skloot was a co-executive producer.
Organizations that have profited from HeLa have since publicly recognized Henrietta Lacks’s contributions to research. The Lacks family has been honored at the Smithsonian Institution and the National Foundation for Cancer Research.
Morgan State University granted Lacks a posthumous honorary degree. In 2010, Dr. Roland Pattillo of Morehouse donated a headstone for Lacks’s unmarked grave.
Legal and Ethical Implications
The HeLa case has raised questions about the legality of using genetic materials without permission. Neither Lacks nor her family granted permission to harvest her cells, which were then cloned and sold.
The California Supreme Court upheld the right to commercialize discarded tissue in the 1990 case Moore v. Regents of the University of California. In 2013, German researchers published the genome of a strain of HeLa cells without permission from the Lacks family.
The Lacks family has had limited success in gaining control of the HeLa strain. In August 2013, an agreement between the family and the National Institutes of Health granted the family acknowledgement in scientific papers and some oversight of the Lacks genome.
QUICK FACTS
- Name: Henrietta Lacks
- Birth Year: 1920
- Birth date: August 1, 1920
- Birth State: Virginia
- Birth City: Roanoke
- Birth Country: United States
- Gender: Female
- Best Known For: Henrietta Lacks is best known as the source of cells that form the HeLa line, used extensively in medical research since the 1950s.
- Industries
- Science and Medicine
- Astrological Sign: Leo
- Interesting Facts
- Cells taken from Henrietta Lacks’s body without her knowledge were used to form the HeLa cell line, which has been used extensively in medical research.
- Death Year: 1951
- Death date: October 4, 1951
- Death State: Maryland
- Death City: Baltimore
- Death Country: United States
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CITATION INFORMATION
- Article Title: Henrietta Lacks Biography
- Author: Biography.com Editors
- Website Name: The Biography.com website
- Url: https://www.biography.com/history-culture/henrietta-lacks
- Access Date:
- Publisher: A&E; Television Networks
- Last Updated: March 3, 2021
- Original Published Date: April 3, 2014
In conclusion, Henrietta Lacks’s story is both tragic and thought-provoking. Her contributions to medical research cannot be overstated, as her cells, known as HeLa cells, have been instrumental in countless scientific breakthroughs and advancements. However, the unethical manner in which her cells were obtained and used raises important questions about medical ethics, patient consent, and racial disparities in healthcare. The injustices that Henrietta Lacks and her family endured highlight the need for greater transparency and respect for patient rights in research and medical practice. It is crucial that we learn from Henrietta’s story and work towards creating a more equitable and ethical healthcare system that values the wellbeing and autonomy of all individuals, regardless of their race or socioeconomic status. Henrietta Lacks’s legacy will continue to serve as a reminder of the importance of informed consent and the ethical responsibility researchers and healthcare professionals have towards their patients.
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